Cortex XDR Prevent – AI-Driven Endpoint Protection That Stops Threats Early
Cyber threats evolve faster than ever, with attacks now occurring up to three times quicker than just a few years ago. Cortex XDR Prevent delivers strong, AI-powered endpoint protection that focuses on stopping threats before they cause damage. Built by Palo Alto Networks, this solution serves organizations that want high-accuracy prevention without the complexity of full detection and response platforms. It protects endpoints across Windows, macOS, Linux, and mobile devices, making it ideal for hybrid and modern IT environments.
Prevention-First Endpoint Security Powered by AI and Machine Learning
Cortex XDR Prevent uses advanced artificial intelligence and machine learning to block threats in real time. It draws intelligence from Unit 42, Palo Alto Networks’ elite threat research team, which analyzes data from more than 70,000 customers worldwide. This global insight allows the platform to stop exploits, malware, ransomware, and fileless attacks before they spread.
A lightweight endpoint agent deploys quickly without requiring system reboots. It continuously monitors processes, analyzes thousands of file attributes, and detects malicious behavior instantly. This prevention-first approach eliminates reliance on signatures and enables protection against zero-day threats as soon as they appear.
Behavioral Protection That Blocks Modern and Zero-Day Attacks
Cortex XDR Prevent actively identifies unusual behaviors that signal malicious activity. Behavioral threat protection spots abnormal patterns early, while exploit prevention shields hundreds of vulnerable processes from known and unknown attacks. Zero-day malware protection blocks previously unseen threats without slowing endpoint performance. Together, these capabilities help organizations reduce risk while maintaining system stability.
Simple, Centralized Endpoint Control Across All Devices
Cortex XDR Prevent combines strong protection with operational simplicity. It includes essential endpoint controls such as device control to manage USB and Bluetooth risks, host firewalls for Windows and macOS, and disk encryption enforcement using BitLocker or FileVault. Organizations can also extend protection to iOS and Android devices for full endpoint coverage.
A single cloud-based management console controls all endpoints, reducing complexity and lowering total cost of ownership. Teams no longer need to manage multiple security tools. The platform scales easily across enterprise environments while keeping administration simple and efficient.
Proven Endpoint Protection Backed by Industry Recognition
Cortex XDR Prevent consistently delivers proven results in real-world testing. It achieved 100% out-of-the-box prevention in the 2025 SE Labs Ransomware test and recorded zero false positives in MITRE ATT&CK Evaluations. Gartner has named Palo Alto Networks a Leader in the Magic Quadrant for Endpoint Protection Platforms for three consecutive years, with Cortex XDR ranking highest in customer recommendations.
This strong track record matters because attackers often exfiltrate data within the first hour of a breach. Cortex XDR Prevent works to stop threats before attackers gain that critical window.
A Strong Foundation for a Modern Security Strategy
Cortex XDR Prevent forms the foundation of a resilient endpoint security strategy. It integrates seamlessly with existing environments and allows organizations to upgrade to Cortex XDR Pro when advanced detection and response capabilities become necessary. For teams that prioritize accurate prevention, low overhead, and operational efficiency, it delivers immediate value.
By reducing alert noise and minimizing manual effort, Cortex XDR Prevent empowers SOC teams to focus on strategic security initiatives while maintaining high system uptime for users.
Smart Endpoint Protection for Long-Term Business Security
Cortex XDR Prevent represents a smart investment in long-term cybersecurity. By stopping threats early, organizations reduce downtime, control costs, and stay ahead of modern adversaries. Whether you run a small business or a global enterprise, this solution adapts to your needs and delivers unmatched endpoint prevention through an easy-to-manage platform.
When prevention matters most, Cortex XDR Prevent helps ensure breaches never get the chance to begin.
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Cortex XDR Prevent datasheet





